Adapalene

Adapalene

Adapalene ( Differin / Adaferin )  is a third-generation topical retinoid primarily used in the treatment of mild-moderate acne, and is also used (off-label) to treat keratosis pilaris as well as other skin conditions. It is effective against acne conditions where comedones are predominant.

Manufacturer: Galderma

Delivery: 10-12 Working Days

Manufacturer: Zydus Healthcare

Availability: In Stock

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Adapalene 0.1% (15gm)

No of Units Price / Unit Price Free Bonus  
2 Tubes $20.00 $40.00
6 Tubes $18.00 $108.00
11 Tubes $16.00 $176.00 + 1 Tube Free
No of Units Price  
2 Tubes 40.0000
6 Tubes 108.0000
11 Tubes + 1 Tube Free 176.0000

Mechanism of action

Unlike tretinoin, adapalene inhibits keratinocyte differentiation. This inhibition of keratinocyte differentiation and proliferation is responsible for adapalene’s comedolytic effect. It has both exfoliating and anti-inflammatory effects. In an in vivo study, adapalene’s ability to reduce comedo formation was demonstrated by a 50–60% reduction in comedo counts compared with vehicle.


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